Modern Anesthetic Agents: Limitations and Advancements

What was the major limitation of diethyl ether, cyclopropane, ethylene, divinyl ether, chloroform, ethyl chloride, trichloroethylene?

A. Solubility

B. Flammability

C. Potency

Answer:

The major limitation of the mentioned anesthetic agents, including diethyl ether and cyclopropane, is their flammability. Modern anesthetics are less flammable and are now preferred.

Modern anesthetic agents have come a long way in terms of safety and efficacy compared to older agents such as diethyl ether, cyclopropane, ethylene, divinyl ether, chloroform, ethyl chloride, and trichloroethylene. One of the major limitations of these older agents was their flammability, which posed significant risks in surgical settings.

Diethyl ether, for example, was widely used for its anesthetic properties in the past but its high flammability made it a hazardous choice. Similarly, cyclopropane, ethylene, divinyl ether, chloroform, ethyl chloride, and trichloroethylene all had issues with flammability, making them less desirable options for anesthesia.

As a result, modern inhalant halogen-containing anesthetic compounds like halothane, enflurane, and isoflurane have become preferred choices in anesthesia practice. These modern agents are less flammable, providing a safer environment for patients undergoing surgery. The development of less flammable anesthetics marks a significant advancement in the field of anesthesia, ensuring better patient outcomes and reducing the risks associated with flammable agents.