What is the predicted frequency of LMLN given the MN blood type example: p=0.5395 and q = 0.4605?

What is the frequency of LMLM given the MN blood type example: p=0.5395 and q = 0.4605?

The predicted frequency of LMLN given the MN blood type example is 2pq. According to the given example, p = 0.5395 and q = 0.4605. The frequency of LMLN given the MN blood type example is calculated as follows: Let's denote L as the dominant allele that encodes for the presence of L antigen on RBCs, while l is the recessive allele that encodes for the absence of L antigen on RBCs. The M and N antigens are under the control of a single gene (LM). p = the frequency of L allele = frequency of LM + LL = frequency of LM + frequency of LL q = the frequency of l allele = frequency of ln + frequency of nn Since LM and LN are codominant, the frequencies of LM and LN can be added to get the frequency of LMLN. Given, p = 0.5395 and q = 0.4605. The genotype frequencies can be calculated using the Hardy-Weinberg equation as: p^2 + 2pq + q^2 = 1 where p^2 = frequency of LL, q^2 = frequency of nn, and 2pq = frequency of LMLN Let's first calculate the genotype frequencies for LM and LN alleles: p + q = 1 0.5395 + 0.4605 = 1 Therefore, the frequency of LM allele = p = 0.5395, and the frequency of LN allele = q = 0.4605. Now, we can use the genotype frequencies to calculate the frequency of LMLM and LMLN: Frequency of LMLM = p^2 = (0.5395)^2 = 0.2912 Frequency of LMLN = 2pq = 2(0.5395)(0.4605) = 0.497 Therefore, the predicted frequency of LMLM given the MN blood type example is 0.2912, and the predicted frequency of LMLN given the MN blood type example is 0.497.

Understanding LMLN Frequency Calculation

The predicted frequency of LMLN given the MN blood type example can be determined by understanding the principles of genetics and allele frequencies. In this case, we are given the frequencies of the p and q alleles, which represent the presence or absence of certain antigens on red blood cells. Genotype Calculation: Using the Hardy-Weinberg equation, we can calculate the genotype frequencies for the LM and LN alleles based on the given p = 0.5395 and q = 0.4605 values. By determining the frequencies of LM and LN, we can then compute the frequencies of LMLM and LMLN. Frequency of LMLM: The frequency of LMLM is determined by squaring the frequency of the L allele (p). In this case, the frequency of LMLM is 0.2912, which indicates the proportion of individuals with the LMLM genotype in the population. Frequency of LMLN: The frequency of LMLN is calculated using the equation 2pq, where p and q represent the frequencies of the L and l alleles, respectively. By multiplying 2pq with the respective allele frequencies, we arrive at a frequency of 0.497 for LMLN. By understanding the genetic relationships between alleles and applying the Hardy-Weinberg equilibrium, we can predict the frequencies of different genotypes in a population. The predicted frequencies provide valuable insights into the distribution of genetic traits and the inheritance patterns of specific alleles.
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