The Genetics of Hemophilia: What Percent of Princess Eugenie and Prince Albert's Children Will Have Hemophilia?

Understanding Hemophilia and Its Genetics

Hemophilia is an X-linked recessive disorder, meaning it is carried on the X chromosome. In the case of Princess Eugenie and Prince Albert, Princess Eugenie is a carrier for hemophilia, with one normal X chromosome and one X chromosome carrying the hemophilia gene. On the other hand, Prince Albert is a hemophiliac, with one X chromosome carrying the hemophilia gene.

Probability of Inheriting Hemophilia

When Princess Eugenie and Prince Albert have children, their sons have a 50% chance of inheriting the hemophilia gene from Princess Eugenie and a 50% chance of inheriting the normal X chromosome from her. Therefore, 50% of their sons will inherit the hemophilia gene and have hemophilia, while the other 50% will inherit the normal X chromosome and not have hemophilia.

On the other hand, their daughters will inherit the normal X chromosome from Princess Eugenie and will be carriers of the hemophilia gene, but will not have hemophilia themselves.

What percent of Princess Eugenie and Prince Albert's children will have hemophilia?

50% of their sons will have hemophilia.